Consistent with previous studies, we found no effect of ADHD on event-based PM performance at this age. This type of ADHD is suggested by the early onset CNS dysfunction. The effect of PAE on PM was not attributable to impaired EF and retrospective memory and was not solely attributable to lower IQ. The ADHD resulting from prenatal alcohol exposure is an acquired form of brain injury. of being diagnosed with attention-deficit hyperactivity disorder (ADHD). Conclusions Fetal alcohol-related impairment in event-based PM was seen in children with FAS/PFAS. Prenatal alcohol exposure did not affect impulsivity in rats that performed. PAE was related to ADHD, but ADHD was not related to PM performance.
This relation was only partially mediated by IQ. PAE was negatively related to PM performance even after adjusting for sociodemographic confounders, EF, and retrospective memory. Results Children with FAS/PFAS made more PM errors than either HE or Control children. Mediation of alcohol effects on PM by IQ, EF, and retrospective memory scores was assessed as was the effect of ADHD on PM performance. The association between a continuous measure of alcohol exposure and PM performance was also examined after controlling for sociodemographic confounders. We examined effects of diagnostic group, cue focality, and task difficulty on PM performance. Methods We administered a computerized PM task to 89 children (Mage = 11.1 years) whose mothers were recruited prenatally: 29 with fetal alcohol syndrome (FAS) or partial FAS (PFAS), 32 nonsyndromal heavily exposed (HE), and 28 Controls. Similarly, a case-control study noted a 2.5 fold increased risk of ADHD associated with prenatal exposure to alcohol (Mick et al., 2002). We investigated event-based PM in children with heavy PAE and the degree to which associations between PAE and PM are influenced by IQ, executive functioning (EF), retrospective memory, and attention deficit/hyperactivity disorder (ADHD). Conversely, other studies have shown an association between symptoms of inattention and impulsivity with prenatal exposure to alcohol (Streissguth et al., 1994 Sampson et al., 1989). 969-978īackground Prenatal alcohol exposure (PAE) is linked to impaired performance on tests of retrospective memory, but prospective memory (PM the ability to remember and act on delayed intentions) has not been examined in alcohol-exposed children. Prenatal alcohol exposure leads to some of the cognitive abnormalities seen in ADHD, and it is in fact considered a risk factor for this disorder (Mick. Alcoholism: Clinical and Experimental Research.
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